Leif Ames

A person with blonde hair and light skin in a black t-shirt points at an image of a large QR code with what appear to be pictographic humans dancing in place of the usual blocky squares between the finding squares.
QR codes can be a handy way to send a link or contact details without all that tedious mucking about with typing in a link, but they aren’t very useful …read more
model / mold / matrix / pattern (HSK 4)

Exclusive: Nvidia, Microsoft and Cisco taskforce urges ministers to offer areas greater benefits from tech infrastructure amid fears of US-style opposition

AI companies have told ministers they have 12 months to head off public opposition to datacentres in the UK or risk US-style protests that could threaten their construction.

Successive dry summers and rising energy bills are increasing public scrutiny of plans for the huge computer warehouses that are used to train and run AI models, says a submission to the Labour government from a group including the AI infrastructure companies Nvidia, Microsoft and Cisco.

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If Flávio Bolsonaro is elected, Brazil’s ecosystems will face collapse. The ruling class would rather burn the world than share it with the poor

However grim the trajectory might seem, I’ve always believed that sense will ultimately prevail. As the great perils of dismantling the living world become increasingly obvious, even the most rapacious exploiters must come round. Nobody wants to live on a dead planet, do they?

There are – or were – signs that this wasn’t just wishful thinking. Since 2015, mostly thanks to China, the area of the planet being reforested has increased, while thanks in large part to Brazil, the global rate of forest destruction has declined. The area of the Brazilian Amazon forest cleared each year is one-sixth of what it was when records began in 1988. In the past four years, as a result of Brazilian government policy, the deforestation rate has fallen by 71%. If Luiz Inácio Lula da Silva is re-elected president on Sunday, the country could reach zero deforestation by 2030. The arc of the moral universe seems to have bent towards justice.

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You Can See Everything, a documentary about the disgraced biotech company founder Elizabeth Holmes, has enjoyed a record-breaking opening in the US. It is a testament to how fascinated we remain by the convicted fraudster, but what is behind the enduring appeal? US technology editor Blake Montgomery tells Madeleine Finlay why Holmes continues to fascinate us, and reflects on whether the Theranos scandal has had a permanent impact on Silicon Valley

Clip: You Can See Everything, A24

‘You can’t make this stuff up’: why we remain fascinated by Elizabeth Holmes

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  • Edwards hits nine threes in 45-point explosion

  • Antetokounmpo scores 35 in first game with Heat

  • Minnesota rout Miami 131-106 in season opener

Anthony Edwards scored 45 points as he and the Minnesota Timberwolves spoiled Giannis Antetokounmpo’s debut with the Miami Heat in an emphatic 131-106 season-opening win on Wednesday night.

Edwards became just the third player in NBA history to record multiple 40-point games in season openers, joining Wilt Chamberlain and Michael Jordan.

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  • Title is club’s first-ever since 2023 founding

  • St Louis clubs have won 11 Open Cups all-time

  • Daniel Edelman nets winner in 5-4 win on penalties

For much of the 20th century, winning the US Open Cup required a team to beat someone from St Louis. The Gateway City was home to many of the nation’s best teams during some ramshackle eras of soccer in the United States, with six different clubs combining for 10 trophy lifts. The most recent came in 1988, when St. Louis Busch Seniors beat San Francisco-based Greek-American AC in the last throes of a tournament history dominated by amateur and semi-pro teams. MLS has won every Open Cup but one since starting play in 1996, and St Louis didn’t have an MLS club until 2023.

From the beginning, club figures spoke of aims to restore the city to soccer prominence. Well, mission accomplished. St Louis City are US Open Cup champions, outlasting the Columbus Crew 5-4 on penalties away from home to end the city’s 38-year wait for a major US soccer title and earn a place in the field for the 2027 Concacaf Champions Cup.

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An anonymous reader quotes a report from The New York Times: For the first time, scientists say they have used viruses designed by artificial intelligence to treat a human patient. Researchers announced on Tuesday that they had administered the virus, known as a phage, to a patient suffering from a deadly bacterial infection. Phages attack bacteria, and the hope is that this one will kill the microbes causing the infection. Radical Numerics, the start-up that created the viruses, posted a technical report about them on its website. But the company declined to provide information about the patient or the doctors running the trial, citing confidentiality requirements. [...] In 2025, researchers at the Arc Institute in Palo Alto, Calif., created an A.I. model called Evo 2, which they trained on millions of DNA sequences, including phage genes. They prompted Evo 2 to make new genomes similar to those in a group of phage species. The A.I. generated 700,000 virus genomes. The team synthesized DNA molecules from 285 genomes and inserted them into bacteria. The researchers found that 16 of the genomes gave rise to viable viruses. Three members of the Evo team, including Dr. Nguyen, left to found Radical Numerics. In June, the company unveiled a new A.I. model, called Omnii, based on some of the same principles as Evo. Omnii can be trained not just on DNA but also on other aspects of biology, such as the structures of proteins and molecules that keep genes turned on or off. The company is now using Omnii to tackle a range of challenges, including designing cancer vaccines and recognizing the risk that a virus may cause a pandemic. Among these efforts is the first trial of A.I.-designed phage therapy. The researchers created variations of a phage called T7. The virus, which only infects E. coli, looks like a microscopic Apollo lunar lander: a ball-shaped protein shell that holds its DNA atop six leglike protrusions. To infect a bacterium, T7 lands on its surface, using its legs to anchor in place. It then injects its DNA into the cell. Omnii generated new viral genes altering the shapes of T7's legs, according to Dr. Nguyen and his colleagues. While some of the new legs were significantly different from natural ones, Omnii's phages could still infect bacteria. Once the researchers were confident their strategy had worked, they partnered with doctors treating a patient with a stubborn E. coli infection. The bacteria had resisted not just antibiotics but all the available phages. The researchers said they had trained Omnii with information about the resistant strain and told it to design T7 phages with legs that could grab onto the bacteria. Once the A.I. generated genomes for new viruses, the scientists said they produced the corresponding DNA molecules and inserted them in bacteria. The bacteria became infected and produced T7 phages that could successfully infect, and kill, other microbes. After running tests to make sure the phages were safe, Radical Numerics presented them to the doctors. The F.D.A. authorized a trial. While the trial was authorized by the FDA, it's worth noting that the research has not yet been peer-reviewed in a scientific journal and there's no guarantee the AI-designed phages will work. However, if it does prove successful, it could help speed phage therapy by cutting down the time it takes to create a new virus tailored to each patient's infection. "We think we can get it done in days," said Dr. Eric Nguyen, the chief executive officer of Radical Numerics.

Read more of this story at Slashdot.

Amazon Web Services logged attempts to leverage the internet-melting PHP2Shell bugs four days ago. They're now being “broadly exploited” across the internet.

Before the advent of effective semiconductor LEDs many display types existed to display things like numbers and other characters. The Nixie tube is a well-known one, along with VFDs and …read more

Democrat, in first interview since pre-dawn raid, denies immigration fraud and says ‘I have a legal right to be a member of Congress’

The Minnesota congresswoman Ilhan Omar denied allegations of immigration fraud in a Wednesday appearance on MS Now, her first interview since federal agents raided her residence last week.

Those in Donald Trump’s orbit – cabinet officials and rightwing influencers alike – have promoted baseless theories about the Democratic congresswoman, accusing Omar of being in a sham marriage with her brother and fudging details of her immigration paperwork.

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