Optogenetic therapy, based on Nobel prize-winning science, involves turning nerve cells on and off using light
A type of gene therapy based on Nobel prize-winning science is safe and can partly restore sight in blind people, researchers have revealed.
The approach, known as optogenetic therapy, harnesses the technique for turning nerve cells on and off using light that scooped the 2026 Nobel prize in physiology or medicine.
Continue reading...Lawyers for Christa Pike, who survived two lethal injections, gave updates on her condition, saying she is severely unwell, and ‘angry and confused about everything right now’. Following a court hearing on Wednesday, a judge ordered Tennessee officials to preserve all evidence from the botched execution
Continue reading...Bernadette Greene-Placentia says she is sharing her story in order to fight for victims of sexual assault
This article contains graphic descriptions of sexual assault.
A congressional candidate in Arizona says she was attacked and raped in August while trying to repair one of her damaged campaign signs.
Information and support for anyone affected by rape or sexual abuse issues is available from the following organizations. In the US, Rainn offers support on 800-656-4673. In the UK, Rape Crisis offers support on 0808 500 2222. In Australia, support is available at 1800Respect (1800 737 732). Other international helplines can be found at ibiblio.org/rcip/internl.html
Continue reading...Trump earlier said he has ‘no regrets’ about endorsing Ken Paxton amid leaked recordings of state attorney general decrying Iran war and high gas prices
Tonight, we’ll have another set of midterm debates. In Iowa, we’ll see the Republican nominee for US Senate, Ashley Hinson, face off against Democrat Josh Turek, a state representative and Paralympian at 8pm ET.
The race has become one of the most competitive of this cycle, despite the fact a Democrat hasn’t won a Senate election in the Hawkeye state since 2008. Turek, however, trails by just a point in a recent New York Times/Siena College poll. And Hinson, who currently serves as a congresswoman, has pushed back on Donald Trump’s agenda of late, as the president’s approval rating sinks to a new low. Hinson has called for an end on the war in Iran, despite consistently voting against House war powers resolutions that would curb military action, and criticizing the president’s recent pause on tariffs for foreign beef imports, which, Hinson argues, will affect the bottom line for the many cattle ranchers in Iowa.
Continue reading...Authorities say they arrested an 18-year-old who was planning a shooting attack at the Mall of America
FBI officials stopped a potential terrorist attack on the Mall of America in Bloomington, Minnesota, authorities announced Wednesday. An 18-year-old was arrested on one count of obtaining a firearm to carry out an act of terrorism.
Sheikhdoon Abdullahi Mohamud had been investigated over the last nearly two years by the FBI. He was arrested Tuesday in a public park after he paid $600 to an undercover FBI employee posing as a member of the Islamic State for an AK-47 and 200 rounds of ammunition, according to the criminal complaint.
Continue reading...President floats firing Chris LaCivita and James Blair over any ‘conflict’ after reports of work in Republika Srpska
Donald Trump distanced himself from two top advisers on Wednesday, claiming he did not have “any idea who else they work for”, after it was reported they spent the weekend assisting a pro-Russia government in the Balkans.
On Truth Social, Trump wrote that Chris LaCivita, the co-manager of his 2024 presidential campaign, and James Blair, a campaign adviser and White House deputy chief of staff on leave of absence, “are outside consultants” and “do not work for me other than as outside consultants”.
Continue reading...Optogenetics revolutionized neuroscience, but its origins come from an entirely brainless organism—an alga.

Lithuania and Canada were also pressured to withdraw, and days before #Disinfo2026, logos were wiped off website
The Trump administration pressured multiple countries to withdraw their sponsorship of a leading European conference on disinformation, with Canada, Lithuania and the EU’s diplomatic service subsequently agreeing to do so, the Guardian understands.
The conference, #Disinfo2026, taking place Wednesday and Thursday, is the annual meetup of Europe’s counter-disinformation community and has drawn hundreds of researchers, journalists, technologists and policymakers to a hotel in Vilnius, Lithuania. It is run by an independent Brussels non-profit, EU Disinfo Lab.
Continue reading...Judge tells Tennessee officials all items in execution room must be saved as Pike remains restrained in hospital bed
A judge ordered Tennessee officials on Wednesday to preserve all evidence related to the botched execution attempt on convicted murderer Christa Pike, as it emerged that the state has refused pleas from medical staff to allow her to be unshackled from her hospital bed.
At a hearing in Nashville on Wednesday, judge I’Ashea Myles said: “Anything that was in the actual room” during the attempted execution a week ago must be preserved by the state, including all drugs, intravenous lines and tubing used in the death chamber.
Continue reading...Pentagon chief tries to play down problems onboard carrier as it returns to dock after 260 days at sea without port call
US defense secretary Pete Hegseth told service members on the USS Abraham Lincoln on Wednesday that their deployment “wasn’t easy” as the carrier prepares to dock after spending over 260 consecutive days at sea without a port call, setting a navy record.
For months, there have been widespread concerns since reports first emerged of supply shortages and deteriorating mental health onboard. In his remarks on Wednesday, however, Hegseth again sought to play down the issues.
Continue reading...Lithuania and Canada were also pressured to withdraw, and days before #Disinfo2026, logos were wiped off website
The Trump administration pressured multiple countries to withdraw their sponsorship of a leading European conference on disinformation, with Canada, Lithuania and the EU’s diplomatic service subsequently agreeing to do so, the Guardian understands.
The conference, #Disinfo2026, taking place Wednesday and Thursday, is the annual meetup of Europe’s counter-disinformation community and has drawn hundreds of researchers, journalists, technologists and policymakers to a hotel in Vilnius, Lithuania. It is run by an independent Brussels non-profit, EU Disinfo Lab.
Continue reading...